Subjects with local allergic rhinitis can be identified by basophil activation test
نویسندگان
چکیده
Background Local allergic rhinitis (LAR) is characterized by negative skin testing and serum specific IgE. Diagnosis is based on nasal provocation test (NPT), very sensitive but time-consuming, and/or presence of local synthesis of specific IgE (sIgE) which shows low sensitivity (22%). The aim of the study was to evaluate the presence of specific D. pteronyssinus (DP) activation of basophils by basophil activation test (BAT) in subjects with confirmed LAR.
منابع مشابه
Utility of the Atopy Patch Test in the Diagnosis of Allergic Rhinitis
Introduction: The diagnostic work-up of allergic rhinitis (AR) is first and foremost based on the combination of clinical history data and results of skin prick tests (SPT). Other tests, including specific IgE measurement, nasal challenge, and, as a third option, component resolved diagnosis or basophil activation test, may be useful when the diagnosis is difficult because of polysensitization ...
متن کاملLocal Allergic Rhinitis.
This review focuses on local allergic rhinitis, a new phenotype of allergic rhinitis, commonly misdiagnosed as nonallergic rhinitis. It has gained attention over last decade and can affect patients from all countries, ethnic groups and ages, impairing their quality of life, and is frequently associated with conjunctivitis and asthma. Diagnosis is based on clinical history, the demonstration of ...
متن کاملPersonality Profiles in Patients With Allergic Rhinitis
Background: Psychological factors can be associated with allergic disorders. However, no particular personality pattern associated with these disorders has yet been identified. Objectives: This study aimed at comparing the personality profiles of patients with perennial allergic rhinitis and normal controls. Materials & Methods: This cross-sectional study was done on 50 adult people with pe...
متن کاملImmunologic responses to the major allergen of Olea Europaea in local and systemic allergic rhinitis subjects
OBJECTIVE To evaluate the in vivo and in vitro responses to nOle e 1 in allergic rhinitis (AR) and local allergic rhinitis (LAR) patients sensitized to olive tree pollen (OL) confirmed by nasal allergen provocation test (NAPT). METHODS Twelve subjects with AR, 12 with LAR and 12 subjects as control group (CG) were selected. Skin testing and NAPT with nOle e 1 were performed. Eosinophilic cati...
متن کاملChanges in basophil activation during immunotherapy with house dust mite and mugwort in patients with allergic rhinitis
Background The basophil activation test (BAT) is a promising tool for monitoring allergen-specific immunotherapy responses. Objective We aimed to investigate the changes in basophil activation in response to the inhalant allergens of house dust mite (HDM) and mugwort pollen during immunotherapy in patients with allergic rhinitis. Methods We enrolled patients with allergic rhinitis who were ...
متن کامل